1:-The most likely primary cause of an acquired form of Nephrogenic Diabetes insipidus is

A:-Down regulation of Aquaporin 2 receptor (AQP2)
B:-Mutations in Vasopressin receptor 2 (V2R)
C:-Reduction in interstitial osmolality
D:-Increased urine production

Correct Answer:- Option-A

2:-Brain Natriuretic Peptide (BNP) is primarily synthesized in

A:-Choroid plexus of ventricles
B:-Cardiac ventricles
C:-Atrial cardiomyocytes
D:-Pericytes in the tubulointerstitial compartment

Correct Answer:- Option-B

3:-Following are the renal complications of Non-steroidal anti-inflammatory drugs EXCEPT

A:-Sodium retention and hypertension
B:-Papillary necrosis

Correct Answer:- Option-D

4:-Barters syndrome is characterized by all EXCEPT

A:-Metabolic alkalosis
D:-Sodium wasting

Correct Answer:- Option-B

5:-In aminoglycoside nephrotoxicity following electrolyte disturbance is found

D:-All of the above

Correct Answer:- Option-D

6:-Which of the following variable is NOT USED to estimate kidney function from Plasma Creatinine in four-variable MDRD (Modification of Diet in Renal Disease) equation ?


Correct Answer:- Option-D

7:-Which of the following statement is NOT TRUE about Vasopressin ?

A:-Synthesized in the posterior pituitary
B:-Secretion is stimulated by an increase in serum osmolality
C:-Acts on renal 𝑉2 receptor
D:-Vasopressin analogues are used in the treatment of Hepatorenal syndrome

Correct Answer:- Option-A

8:-Mark the best response from the statement below on medication associated hyperkalemia.

A:-Cyclosporine and Tacrolimus cause hyperkalemia by causing hyporeninemic hypoaldosteronism
B:-Amiloride cause hyperkalemia by inhibiting ENaC activity in distal nephron
C:-Pentamidine block ENaC receptor
D:-All the above statements are true

Correct Answer:- Option-D

9:-The drug of choice for treatment of ethylene glycol induced acidosis is

A:-Intravenous saline administration
B:-Intravenous Bicarbonate therapy
C:-Intravenous Fomepizole
D:-Intravenous Thiamine

Correct Answer:- Option-C

10:-Drug induced Distal RTA

A:-Amphotericin B
D:-All of the above

Correct Answer:- Option-A